Prilosec OTC Kidney Failure

Prilosec OTC Kidney Failure
People who take Prilosec OTC may be at risk for nephritis or chronic kidney disease, both of which can lead to renal (kidney) failure. Though proton pump inhibitors like Prilosec OTC are intended to be taken for only a short time, many people actually use the drugs for extended periods. Recent studies indicate that such prolonged use may increase the likelihood of serious kidney damage.

Prilosec OTC Lawsuit Reviews

The nationwide law firm of Bernstein Liebhard LLP is now offering free legal reviews to Prilosec OTC users who were diagnosed with serious kidney complications, including renal failure and chronic kidney disease. If you think you or a loved might be eligible to file a Prilosec lawsuit, please call (888) 994-5118 to get in touch with our legal team today.

What is Prilosec OTC?

Prilosec, the original prescription proton pump inhibitor, was introduced in 1988. In 2000, Prilosec OTC became available over-the-counter. By 2013, Prilosec OTC ranked as one of the top five over-the-counter medications, with sales reaching nearly $400 million.

Prilosec OTC delivers the same medicine at the same dose as 20 mg prescription Prilosec. It is indicated for people with frequent heartburn, defined as heartburn occurring two or more days a week. Prescription Prilosec is also indicated to heal erosive esophagitis (damage to the esophagus caused by stomach acid), and for the treatment of gastric ulcers caused by H. pylori infection.

Prilosec, Prilosec OTC and other proton pump inhibitors work by shutting down active pumps in the stomach that produce gastric acid.

Prilosec Kidney Failure and Disease Warnings

It’s long been known that heartburn drugs like Prilosec can cause acute kidney damage in people with pre-existing kidney disease. But recent studies suggest that long-term use of the drugs might be associated with kidney failure and chronic kidney disease in previously healthy patients.

  • December 2014: The U.S. Food & Drug Administration (FDA) required the manufacturers of prescription proton pump inhibitors to add new warnings to their drugs’ labels regarding acute interstitial nephritis. This condition results in renal inflammation, and can lead to kidney failure if not treated.
  • January 2016: A study published in JAMA: Internal Medicine suggested that patients who use these popular heart burn drugs might face a 20 to 50% higher risk of kidney disease. Twice daily use was linked to a 46% increased risk, while those who used proton pump inhibitors once per day faced a 15% increased risk. Drugs like Prilosec were also associated with a 39% higher risk of chronic kidney disease compared to H2 blockers like Zantac. Read More
  • April 2016: A study published in the Journal of the American Society of Nephrology suggested that patients who take drugs like Prilosec are 96% more likely to develop kidney failure and 28% more likely to develop chronic kidney disease. The findings also indicated that the overall risk increases with higher doses and longer duration of use. Read More

Learn More about Filing a Prilosec Lawsuit

Bernstein Liebhard LLP offers free legal reviews to individuals who may have suffered serious kidney damage, including renal failure and chronic kidney disease, due to their use of Prilosec OTC or prescription Prilosec. To schedule your review, please call (888) 994-5118.

  1. Procter & Gamble (N.D.) “Frequently Asked Questions for Healthcare Professionals” http://www.prilosecotc.com/en-us/hcp/faq
  2. Public Citizen (2014) “FDA’s Partial Approval of Public Citizen’s Petition for Stronger Warnings on Certain Proton Pump Inhibitor Products Comes Too Late” http://www.citizen.org/pressroom/pressroomredirect.cfm?ID=4324
  3. JASN (2016) “Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD” http://jasn.asnjournals.org/content/early/2016/04/13/ASN.2015121377.abstract
  4. JAMA: Internal Medicine (2016) “Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease” http://archinte.jamanetwork.com/article.aspx?articleid=2481157
Last Modified: May 2, 2016

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