Acute interstitial nephritis is a sudden form of kidney inflammation that can affect people taking PrevAcid. If not recognized and treated, the condition may progress to kidney disease and renal failure.
Proton pump inhibitors like PrevAcid can contribute to the development of acute interstitial nephritis, a condition characterized by a sudden inflammation of the kidney tubules. In fact, one study from 2014 found that these heart burn medications were the most common cause of the condition in an outpatient setting.
In 2014, the U.S. Food & Drug Administration (FDA) added information about nephritis to the labels of all prescription proton pump inhibitors, including PrevAcid. The agency did so in response to a petition filed by Public Citizen that demanded stronger warnings and patient medication guides for the entire class of heart burn drugs. However, reports of patients who developed the condition while using proton pump inhibitors began appearing in the medical literature as early as 1992 . Read More.
Interstitial nephritis can cause mild to severe kidney problems. About 50% of those affected experience decreased urine output. Other symptoms may include:
When a drug such as PrevAcid is suspected to be the cause of acute kidney inflammation, cessation of the medication may alleviate symptoms. In serious cases, dialysis may be required for a period of time. Anti-inflammatory drugs, such as corticosteroids, can be helpful.
Complications associated with nephritis include metabolic acidosis, chronic kidney failure and end-stage kidney disease. Older people are more likely to experience these serious problems.
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