PrevAcid Kidney Failure

PrevAcid Kidney Failure
It was already known that PrevAcid  and similar heartburn drugs may  cause acute kidney damage in people with pre-existing renal (kidney) disease. Now new studies suggest that long-term use of proton pump inhibitors, including PrevAcid,  might be associated with renal failure and chronic kidney disease in previously healthy patients.

PrevAcid Lawsuit Reviews

The nationwide law firm of Bernstein Liebhard LLP is now offering free legal reviews to PrevAcid users who were diagnosed with serious kidney complications, including renal failure and chronic kidney disease. If you think you or a loved might be eligible to file a PrevAcid lawsuit, please call (888) 994-5118 to get in touch with our legal team today.

What is PrevAcid?

PrevAcid is a  proton pump inhibitor marketed by Takeda Pharmaceuticals. At one point, the medication was the company’s top-selling prescription drug, with annual sales of $3 billion.  PrevAcid 24HR is sold without a prescription. Like other proton pump inhibitors, PrevAcid relieves acid reflux by shutting down active pumps in the stomach that produce gastric acid.

PrevAcid Kidney Warnings and Studies

In recent years, the kidney side effects potentially associated with the use of PrevAcid and other proton pump inhibitors have raised concern:

  • December 2014: The U.S. Food & Drug Administration (FDA) required the manufacturers of prescription proton pump inhibitors to add new warnings to their drugs’ labels regarding acute interstitial nephritis. This condition results in renal inflammation, and can lead to kidney failure if not treated.
  • January 2016: A study published in JAMA: Internal Medicine suggested that patients who use PrevAcid and similar heart burn drugs might face a 20 to 50% higher risk of kidney disease. Twice daily use was linked to a 46% increased risk, while those who used proton pump inhibitors once per day faced a 15% increased risk. Proton pump inhibitors were also associated with a 39% higher risk of chronic kidney disease compared to H2 blockers like Zantac. Read More
  • April 2016: A study published in the Journal of the American Society of Nephrology suggested that patients who take drugs like PrevAcid are 96% more likely to develop kidney failure and 28% more likely to develop chronic kidney disease. The findings also indicated that the overall risk increases with higher doses and longer duration of use. Read More

The reduction of gastric acid that occurs with proton pump inhibitors can inhibit the body’s ability to absorb magnesium, which plays an important role in renal function. A deficiency of this mineral could result in kidney damage. Repeated bouts of inflammation can also harm the kidneys over time. In fact, roughly 50% patients who experience acute interstitial nephritis will develop kidney failure. Iti is also estimated that  15% of hospitalizations for renal failure are the result of nephritis.

Learn More about Filing a PrevAcid Lawsuit

Bernstein Liebhard LLP offers free legal reviews to individuals who may have suffered serious kidney damage, including renal failure and chronic kidney disease, due to their use of PrevAcid. To schedule your review, please call (888) 994-5118.

  1. Public Citizen (2014) “FDA’s Partial Approval of Public Citizen’s Petition for Stronger Warnings on Certain Proton Pump Inhibitor Products Comes Too Late” http://www.citizen.org/pressroom/pressroomredirect.cfm?ID=4324
  2. JASN (2016) “Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD” http://jasn.asnjournals.org/content/early/2016/04/13/ASN.2015121377.abstract
  3. JAMA: Internal Medicine (2016) “Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease” http://archinte.jamanetwork.com/article.aspx?articleid=2481157
Last Modified: May 2, 2016

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