A California man has filed a lawsuit against the manufactures of Nexium 24HR for side effects he claims resulted from long-term use of the popular heart burn drug.
The case, which is pending in the multidistrict litigation now underway in the U.S. District Court, District of New Jersey, alleges that Nexium 24HR contributed to the plaintiffs’ acute kidney injury and left him in need of dialysis. (Case No. Case 2:18-cv-13500)
The Nexium 24HR lawsuit also appears to be the first filing to claim gastric cancer as a consequence of long-term proton pump inhibitor use.
Nexium 24HR is the OTC version of Nexium, and ranks as one of the most popular proton pump inhibitors on the market. Other heart burn drugs in this class include PrevAcid, PrevAcid 24HR, Prilosec, Prilosec OTC, Protonix, and Dexilant.
Prescription proton pump inhibitors are taken by some 13 million Americans annually to treat the effects of GERD and other acid-related gastric disorders. Millions more rely on OTC brands.
Their popularity has lulled many proton pump inhibitors users into a sense of complacency and few give any thought to their potential side effects. However, recent studies have linked long-term use to a range of adverse health consequences including gastric cancer and kidney damage.
Just last year, for example, a study in the medical journal Gut suggested that individuals who used Nexium and similar drugs for an extended period of time were more than twice as likely to develop gastric cancer compared to those who took another class of heart burn drug.
Other studies have found that long-term proton pump inhibitor use increases the risk of kidney failure by as much as 96% and the risk of chronic kidney disease by as much as 50%.
There are currently more than 4,500 proton pump inhibitor lawsuits pending in the District of New Jersey, the vast majority of which were filed on behalf of individuals who are alleged to have developed kidney problems – acute kidney injury, kidney failure, acute interstitial nephritis, and chronic kidney disease – in connection with long-term use.
Among other things, plaintiffs contend that the proton pump inhibitor manufacturers have received hundreds of reports linking their products to serious renal side effects since the medications first came on the market. They accuse the drug makers of concealing these reports from the public and failing to warn patients and doctors about the risks of long-term proton pump inhibitor use.