Prilosec Lawsuit Alleges Kidney Side Effects Led to New York Woman’s Wrongful Death

Published on September 5, 2017 by Laurie Villanueva

The family of a New York woman who died from complications related to kidney failure is pursuing a wrongful death lawsuit against the manufacturers of Prilosec.

According to a complaint filed with the U.S. District Court, District of New Jersey, on August 23rd, Mary Manley was prescribed Prilosec on numerous occasions, beginning as early as 2006 and through 2015. The lawsuit charges that Manley’s use of Prilosec caused her to develop worsening Chronic Kidney Disease, and ultimately, fatal renal failure.

Manley died in August 2015, after being diagnosed with multi-organ failure, respiratory arrest and healthcare associated pneumonia.

“During the period in which Prilosec has been sold in the United States, hundreds of reports of injury have been submitted to the FDA regarding the ingestion of Prilosec and other PPIs. Defendants have had notice of serious adverse health outcomes through case reports, clinical studies and post-market surveillance,” the complaint states. “Specifically, Defendants have received numerous case reports of several types of kidney injuries in patients who ingested Prilosec, including: Acute Interstitial Nephritis (“AIN”); Chronic Kidney Disease (“CKD”); Renal/Kidney Failure; and Acute Kidney Injury (“AKI”).”

The lawsuit further asserts that Manley would have never used Prilosec had AstraZeneca provided her and her doctors with adequate warnings regarding its risk and points out that numerous safer alternatives exists for treating heartburn.

‘Despite clear knowledge that Prilosec causes a significantly increased risk of CKD, AKI and other renal impairment, Defendants continue to market and sell Prilosec without warning consumers or healthcare providers of the significant risks to the kidneys,” the complaint continues.

Proton Pump Inhibitor Litigation

Millions of Americans turn to Prilosec and other proton pump inhibitors every year to cope with symptoms of GERD and other acid-related digestive disorders. Because drugs like Nexium, Prilosec, and PrevAcid have become so common, few people worry about the side effects potentially associated with their use. However, a growing body of research suggests that long-term treatment with proton pump inhibitors may harm the kidneys, leading to Chronic Kidney Disease, acute interstitial nephritis, acute kidney injury, and kidney failure.

Court documents indicate that at nearly 200 proton pump inhibitor lawsuits involving kidney failure and other renal complications have been filed in federal courts against the manufacturers of Prilosec, PrevAcid, Nexium, Dexilant, and Protonix.

In August, the U.S. Judicial Panel on Multidistrict Litigation (JPML) centralized all federally-filed kidney injury lawsuits filed against proton pump inhibitor manufacturers in the District of New Jersey, to allow what is likely to be a large number of cases to undergo coordinated discovery and other pretrial proceedings.

The federal multidistrict is scheduled to convene its initial conference on September 12th.

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