New Pretrial Orders have been filed by the federal court overseeing hundreds of product liability claims involving the chemotherapy drug Taxotere and its alleged potential to cause permanent alopecia.
Pretrial Order No. 49, filed in the U.S. District Court, Eastern District of Louisiana on July 6th, adopts a protocol for the production of electronically stored information (ESI). The protocol addresses the scope of ESI discovery, search methodology, timing of discovery, format of production and other matters. It also directs each of the parties to designate a liaison to coordinate all ESI requests and responses.
Pretrial Order No. 50 was also issued on July 6th and adopts a Protective Order that sets forth guidelines governing the disclosure of certain confidential information, including.
Court records indicate that more than 1,100 Taxotere lawsuits are currently undergoing coordinated pretrial proceedings in the Eastern District of Louisiana. All federally-filed hair loss claims involving the cancer drug were transferred to Louisiana last October, after the U.S. Judicial Panel on Multidistrict Litigation determined that the growing docket would benefit from consolidation.
Taxotere was brought to market by Sanofi-Aventis in 1996, and was initially approved to treat breast cancer. Its approved indications have since been expanded to several other cancers. It wasn’t until December 2015, however, that the U.S. Taxotere label was updated to include mention of permanent hair loss as a potential side effect.
Alopecia often accompanies chemotherapy. However, plaintiffs in Taxotere lawsuits charge that it is far more likely to cause permanent hair loss compared to other, equally effective chemotherapy agents. Among other things, they note that doctors and patients were informed of the potential for permanent hair loss in 2005, while the Canadian label underwent a similar modification in 2012. By contrast, the U.S. prescribing information only included a vaguely worded and insufficient statement that “hair generally grows back.”
According to Taxotere lawsuits, permanent alopecia associated with its use results in baldness, as well as the loss of eyelashes, eyebrows and pubic hair. Plaintiffs claim that Sanofi-Aventis has long been aware of this potential side effect, and cite several studies that have suggested a link between Taxotere and persistent hair loss, including: